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Asciminib

CAS 2119669-71-3C20H19Cl2F2N5O3MW 486.3

Asciminib (CAS No. 2119669-71-3) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Product Overview

CAS Number2119669-71-3
Molecular FormulaC20H19Cl2F2N5O3
Molecular Weight486.3
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Applications

Pharmaceutical Intermediates & APIs

Packaging & Storage

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
ShippingStandard chemical transport
SampleAvailable on request
Lead TimeIn stock / per order

Quality & Documentation

COA (Certificate of Analysis) is provided with every batch. MSDS/technical data sheets and third-party test reports are available on request. Purity and packaging are subject to batch COA and order confirmation.

Frequently Asked Questions

What is the CAS number of Asciminib?

The CAS number of Asciminib is 2119669-71-3.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Asciminib?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Asciminib or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Asciminib · CAS 2119669-71-3 · C20H19Cl2F2N5O3. UNII C5U34S9XFV.

Identification

CAS Registry Number2119669-71-3
PubChem CID133082086
Molecular formulaC20H19Cl2F2N5O3
IUPAC nameN-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;hydrochloride
UNII (FDA)C5U34S9XFV

Computed Descriptors

Molecular Weight486.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass485.0833012
Monoisotopic Mass485.0833012
Topological Polar Surface Area103
Heavy Atom Count32
Formal Charge0
Complexity626

Documented Uses

  • Asciminib hydrochloride is approved to treat adults with:
  • • chronic myelogenous leukemia (CML) that is in chronic phase and is Philadelphia chromosomepositive. It is used:
  • • in patients who have received at least two tyrosine kinase inhibitors
  • • in patients whose CML has the T315I mutation
  • • in patients with newly diagnosed CML¹
  • ¹This use is approved under FDA’s Accelerated Approval Program. As a condition of approval, confirmatory trial(s) must show that asciminib hydrochloride provides a clinical benefit in these patients.Asciminib hydrochloride is also being studied in the treatment of other types of cancer.

Synonyms

Asciminib hydrochloride; 2119669-71-3; ABL001-AAA; C5U34S9XFV; RefChem:58303; Asciminib (hydrochloride); Scemblix; Asciminib hydrochloride [USAN]; UNII-C5U34S9XFV; Asciminib HCl; Scemblix (TN); Asciminib hydrochloride [MI]; orb1686815; orb1940871; CHEMBL4297220; SCHEMBL22656445

Frequently Asked Questions

What are the CAS number and molecular formula of Asciminib?

CAS 2119669-71-3; molecular formula C20H19Cl2F2N5O3; molecular weight — g/mol.

What other names is Asciminib known by?

Asciminib hydrochloride, 2119669-71-3, ABL001-AAA, C5U34S9XFV, RefChem:58303, Asciminib (hydrochloride).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

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