Aprindine HCL

Description

Aprindine HCL · CAS 33237-74-0 · C22H30N2. UNII 5Y48085P9Q. Melting Point: 120-121 °C; Melting Point: 120 - 121 °C; Solubility: 7.82e-03 g/L.

Identification

CAS Registry Number	33237-74-0
PubChem CID	2218
Molecular formula	C22H30N2
IUPAC name	N'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N'-phenylpropane-1,3-diamine
UNII (FDA)	5Y48085P9Q

Computed Descriptors

Molecular Weight	322.5
XLogP3	5.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	8
Exact Mass	322.240898965
Monoisotopic Mass	322.240898965
Topological Polar Surface Area	6.5
Heavy Atom Count	24
Formal Charge	0

Physical & Chemical Properties

Melting Point	120-121 °C
Melting Point	120 - 121 °C
Solubility	7.82e-03 g/L
LogP	4.86

Physical description & handling notes

• Solid

Documented Uses

• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.
• C01B - Antiarrhythmics, class i and iii
• C01BB - Antiarrhythmics, class ib
• QC01B - Antiarrythmics, class i and iii
• QC01BB - Antiarrhythmics, class ib

Synonyms

APRINDINE; 37640-71-4; Aprindina; Aprindinum; COMPOUND 99170; COMPOUND-99170; 1,3-Propanediamine, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-; DTXSID3022615; 5Y48085P9Q; (3-((2,3-dihydro-1H-inden-2-yl)(phenyl)amino)propyl)diethylamine; {3-[(2,3-dihydro-1H-inden-2-yl)(phenyl)amino]propyl}diethylamine; RefChem:388807; DTXCID702615; Aprindin; Aprinidine; Aprindinum [INN-Latin]

Frequently Asked Questions

What are the CAS number and molecular formula of Aprindine HCL?

CAS 33237-74-0; molecular formula C22H30N2; molecular weight — g/mol.

What other names is Aprindine HCL known by?

APRINDINE, 37640-71-4, Aprindina, Aprindinum, COMPOUND 99170, COMPOUND-99170.

What are the key physical properties of Aprindine HCL?

Melting Point: 120-121 °C; Melting Point: 120 - 121 °C; Solubility: 7.82e-03 g/L; LogP: 4.86.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.