安普那韦（CAS 161814-49-9）：分子式 C25H35N3O6S、分子量 505.6。
| CAS号 | 161814-49-9 |
|---|---|
| 分子式 | C25H35N3O6S |
| 分子量 | 505.6 |
| LogP | log Kow = 2.2 @ 25 °C /Estimated/ |
| 应用领域 | Uses: MEDICATION、Antiviral、For the treatment of HIV-1 infection in combination with other antiretroviral agents.、Methods of Manufacturing: Preparation: ... R.D. Tung et al、US 5585397 (1994、1996 both to Vertex)、Formulations、Preparations: Oral: Capsules、liquid-filled、50 mg、Agenerase (with propylene glycol 19 mg and vitamin E 36 units)、GlaxoSmithKline、150 mg、Agenerase (with propylene glycol and vitamin E 109 units)、GlaxoSmithKline.Solution: 15 mg、ml、Agenerase (with propylene glycol 550 mg、and vitamin E 46 units、ml) |
登记用途：Uses: MEDICATION、Antiviral、For the treatment of HIV-1 infection in combination with other antiretroviral agents.、Methods of Manufacturing: Preparation: ... R.D. Tung et al、US 5585397 (1994、1996 both to Vertex)、Formulations、Preparations: Oral: Capsules、liquid-filled、50 mg、Agenerase (with propylene glycol 19 mg and vitamin E 36 units)、GlaxoSmithKline、150 mg、Agenerase (with propylene glycol and vitamin E 109 units)、GlaxoSmithKline.Solution: 15 mg、ml、Agenerase (with propylene glycol 550 mg、and vitamin E 46 units、ml)。
安普那韦 是一种化工化合物，登记 CAS 号为 161814-49-9，分子式 C25H35N3O6S（分子量 505.6）。
登记 CAS 号：161814-49-9
其分子式 C25H35N3O6S 由 25 个碳、35 个氢、3 个氮、6 个氧、1 个硫 组成。
别名/同义词：安普那韦 · AMPRENAVIR
安普那韦 的 CAS 登记号为 161814-49-9。
分子式 C25H35N3O6S，分子量 505.6。
别名/同义词：安普那韦、AMPRENAVIR。
登记用途：Uses: MEDICATION、Antiviral、For the treatment of HIV-1 infection in combination with other antiretroviral agents.、Methods of Manufacturing: Preparation: ... R.D. Tung et al、US 5585397 (1994、1996 both to Vertex)、Formulations、Preparations: Oral: Capsules、liquid-filled、50 mg、Agenerase (with propylene glycol 19 mg and vitamin E 36 units)、GlaxoSmithKline、150 mg、Agenerase (with propylene glycol and vitamin E 109 units)、GlaxoSmithKline.Solution: 15 mg、ml、Agenerase (with propylene glycol 550 mg、and vitamin E 46 units、ml)。
安普那韦（CAS 161814-49-9）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 161814-49-9 |
|---|---|
| PubChem CID | 65016 |
| Molecular formula | C25H35N3O6S |
| IUPAC name | [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate |
| UNII (FDA) | 5S0W860XNR |
| Molecular Weight | 505.6 |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 12 |
| Exact Mass | 505.22465702 |
| Monoisotopic Mass | 505.22465702 |
| Topological Polar Surface Area | 140 |
| Heavy Atom Count | 35 |
| Solubility | In water, 40 mg/l @ 25 °C |
|---|---|
| Solubility | 4.91e-02 g/L |
| Vapor Pressure | 9.9X10-18 mm Hg @ 25 °C /Estimated/ |
| LogP | log Kow = 2.2 @ 25 °C /Estimated/ |
amprenavir; 161814-49-9; Agenerase; VX-478; Prozei; 141W94; KVX-478; Vertex VX478; VX 478; 5S0W860XNR; CHEBI:40050; J05AE05; Tetrahydro-3-furyl N-(3-(4-amino-N-isobutylbenzenesulfonamido)-1-benzyl-2-hydroxypropyl)carbamate; KVX 478; DTXSID5046061; Amprenavirum
| Reported hazard statements | H351 (100%), H361 (100%), H412 (100%) |
|---|
H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]
H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
AMPRENAVIR · CAS 161814-49-9 · C25H35N3O6S. UNII 5S0W860XNR. Solubility: In water, 40 mg/l @ 25 °C; Solubility: 4.91e-02 g/L; Vapor Pressure: 9.9X10-18 mm Hg @ 25 °C /Estimated/.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: AMPRENAVIR