AMPRENAVIR (CAS 161814-49-9) — formula C25H35N3O6S, molecular weight 505.6; category pharmaceutical intermediates and APIs.
AMPRENAVIR (CAS 161814-49-9) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C25H35N3O6S comprises 25 C, 35 H, 3 N, 6 O, 1 S atoms. Its molecular weight is about 505.6. Reported physicochemical data: LogP about log Kow = 2.2 @ 25 °C /Estimated/. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 161814-49-9 |
|---|---|
| Molecular Formula | C25H35N3O6S |
| Molecular Weight | 505.6 |
| LogP | log Kow = 2.2 @ 25 °C /Estimated/ |
| Applications | MEDICATION, Antiviral, For the treatment of HIV-1 infection in combination with other antiretroviral agents, Methods of Manufacturing: Preparation: ... R.D. Tung et al, US 5585397 (1994, 1996 both to Vertex) |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: MEDICATION, Antiviral, For the treatment of HIV-1 infection in combination with other antiretroviral agents, Methods of Manufacturing: Preparation: ... R.D. Tung et al, US 5585397 (1994, 1996 both to Vertex).
AMPRENAVIR is a pharmaceutical intermediate or API compound with CAS registry number 161814-49-9 and molecular formula C25H35N3O6S (molecular weight 505.6), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 161814-49-9
Its molecular formula C25H35N3O6S comprises 25 C, 35 H, 3 N, 6 O, 1 S atoms.
Also known as: AMPRENAVIR · 安普那韦
Category: pharmaceutical intermediates and APIs
The CAS registry number of AMPRENAVIR is 161814-49-9.
Molecular formula C25H35N3O6S, molecular weight 505.6.
It is also registered under: AMPRENAVIR, 安普那韦.
Recorded applications: MEDICATION, Antiviral, For the treatment of HIV-1 infection in combination with other antiretroviral agents, Methods of Manufacturing: Preparation: ... R.D. Tung et al, US 5585397 (1994, 1996 both to Vertex).
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for AMPRENAVIR (CAS 161814-49-9), compiled from public chemistry databases.
| CAS Registry Number | 161814-49-9 |
|---|---|
| PubChem CID | 65016 |
| Molecular formula | C25H35N3O6S |
| IUPAC name | [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate |
| UNII (FDA) | 5S0W860XNR |
| Molecular Weight | 505.6 |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 12 |
| Exact Mass | 505.22465702 |
| Monoisotopic Mass | 505.22465702 |
| Topological Polar Surface Area | 140 |
| Heavy Atom Count | 35 |
| Solubility | In water, 40 mg/l @ 25 °C |
|---|---|
| Solubility | 4.91e-02 g/L |
| Vapor Pressure | 9.9X10-18 mm Hg @ 25 °C /Estimated/ |
| LogP | log Kow = 2.2 @ 25 °C /Estimated/ |
amprenavir; 161814-49-9; Agenerase; VX-478; Prozei; 141W94; KVX-478; Vertex VX478; VX 478; 5S0W860XNR; CHEBI:40050; J05AE05; Tetrahydro-3-furyl N-(3-(4-amino-N-isobutylbenzenesulfonamido)-1-benzyl-2-hydroxypropyl)carbamate; KVX 478; DTXSID5046061; Amprenavirum
| Reported hazard statements | H351 (100%), H361 (100%), H412 (100%) |
|---|
H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]
H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
AMPRENAVIR · CAS 161814-49-9 · C25H35N3O6S. UNII 5S0W860XNR. Solubility: In water, 40 mg/l @ 25 °C; Solubility: 4.91e-02 g/L; Vapor Pressure: 9.9X10-18 mm Hg @ 25 °C /Estimated/.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 安普那韦