Amines, C12-16-alkyldimethyl, N-oxides

Independent reference data for Amines, C12-16-alkyldimethyl, N-oxides (CAS 85408-49-7), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

Present in marine organisms; Used in organic synthesis (oxidizing agent); [Merck Index] Used to make quaternary ammonium compounds, as an insect attractant, and a warning agent for flammable gas; [ChemIDplus] Used as flavoring agent or adjuvant; [FDA]TMAO is produced endogenously in the body. High levels are found in fish. It is a uremic toxic and an atherotoxin or atherogenic. It is also an osmolyte.

Synonyms and trade names

TRIMETHYLAMINE N-OXIDE; Trimethylamine oxide; 1184-78-7; N,N-dimethylmethanamine oxide; Triox; Trimethyloxamine; TMAO; N,N-Dimethylmethanamine N-oxide; Methanamine, N,N-dimethyl-, N-oxide; trimethylammonium oxide; (CH3)3NO; FLD0K1SJ1A; NSC-408426; CHEBI:15724; FEMA NO. 4245; RefChem:933449

Regulatory listings held on file

Regulatory & Food Contact	EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent No safety concern at current levels of intake when used as a flavouring agent ">TRS 952-JECFA 69/155

GHS hazard classification

Reported hazard statements	H302 (71.8%), H315 (100%), H318 (100%), H400 (100%), H411 (55.9%), H332 (31.5%), H319 (64.1%), H335 (63%)

H302 (71.8%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

What the public record says

Amines, C12-16-alkyldimethyl, N-oxides · CAS 85408-49-7 · C3H9NO. UNII FLD0K1SJ1A. Melting Point: 95 - 99 °C; Solubility: 454 mg/mL; LogP: -2.570.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.