氨磷汀（CAS 20537-88-6）：分子式 C5H15N2O3PS、分子量 214.23。
| CAS号 | 20537-88-6 |
|---|---|
| 分子式 | C5H15N2O3PS |
| 分子量 | 214.23 |
| LogP | -1.9 |
| 应用领域 | Uses: To reduce the cumulative renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer ... reduce the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer、THERAP CAT: Radioprotective agent、Methods of Manufacturing: Preparation: J.R. Piper、T.P. Johnston、US 3892824 (1975 to Southern Research Institute)、1、3-Propanediamine is monoalkylated with 2-chloroethanol to form 2-[3-(aminopropyl)amino]ethanol and the free OH converted to Br by use of HBr. Treating the resulting alkyl bromide with sodium thiophosphate、followed by acidification affords the product.、Formulations、Preparations: Ethyol |
登记用途：Uses: To reduce the cumulative renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer ... reduce the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer、THERAP CAT: Radioprotective agent、Methods of Manufacturing: Preparation: J.R. Piper、T.P. Johnston、US 3892824 (1975 to Southern Research Institute)、1、3-Propanediamine is monoalkylated with 2-chloroethanol to form 2-[3-(aminopropyl)amino]ethanol and the free OH converted to Br by use of HBr. Treating the resulting alkyl bromide with sodium thiophosphate、followed by acidification affords the product.、Formulations、Preparations: Ethyol。
氨磷汀 是一种化工化合物，登记 CAS 号为 20537-88-6，分子式 C5H15N2O3PS（分子量 214.23）。
登记 CAS 号：20537-88-6
其分子式 C5H15N2O3PS 由 5 个碳、15 个氢、2 个氮、3 个氧、1 个磷、1 个硫 组成。
别名/同义词：氨磷汀 · Amifostine
氨磷汀 的 CAS 登记号为 20537-88-6。
分子式 C5H15N2O3PS，分子量 214.23。
别名/同义词：氨磷汀、Amifostine。
登记用途：Uses: To reduce the cumulative renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer ... reduce the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer、THERAP CAT: Radioprotective agent、Methods of Manufacturing: Preparation: J.R. Piper、T.P. Johnston、US 3892824 (1975 to Southern Research Institute)、1、3-Propanediamine is monoalkylated with 2-chloroethanol to form 2-[3-(aminopropyl)amino]ethanol and the free OH converted to Br by use of HBr. Treating the resulting alkyl bromide with sodium thiophosphate、followed by acidification affords the product.、Formulations、Preparations: Ethyol。
氨磷汀（CAS 20537-88-6）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 20537-88-6 |
|---|---|
| PubChem CID | 2141 |
| 分子式 | C5H15N2O3PS |
| IUPAC 名称 | 2-(3-aminopropylamino)ethylsulfanylphosphonic acid |
| UNII（FDA） | ILA426L95O |
| Molecular Weight | 214.23 |
|---|---|
| XLogP3 | -4.5 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 7 |
| Exact Mass | 214.05410052 |
| Monoisotopic Mass | 214.05410052 |
| Topological Polar Surface Area | 121 |
| Heavy Atom Count | 12 |
| Solubility | 1000 |
|---|---|
| Solubility | 1.87e+01 g/L |
| Solubility | 95% Ethanol < 0.01 (mg/mL) |
| Solubility | Chloroform < 0.01 (mg/mL) |
| Solubility | Toluene < 0.01 (mg/mL) |
| LogP | -1.9 |
amifostine; 20537-88-6; Ethiofos; Gammaphos; Ethyol; Apaetp; Aminopropylaminoethyl thiophosphate; Ethiofos Anhydrous; Amifostine Anhydrous; YM-08310; Amifostina; NSC-296961; WR 2721; WR-2721; DTXSID8022585; NSC296961
| 已通报的危害声明 | H302 (100%) |
|---|
氨磷汀 · CAS 20537-88-6 · C5H15N2O3PS. UNII ILA426L95O. Solubility: 1000; Solubility: 1.87e+01 g/L; Solubility: 95% Ethanol < 0.01 (mg/mL).
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Amifostine