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Alendronic Acid

CAS 66376-36-1C4H13NO7P2MW 249.10

Alendronic Acid (CAS No. 66376-36-1) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of per batch COA (not published). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Product Overview

CAS Number66376-36-1
Molecular FormulaC4H13NO7P2
Molecular Weight249.10
Melting Point235
LogP-6.5
Purityper batch COA (not published)
Packagingper order / batch confirmation (not published)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Applications

Organic Chemicals

Packaging & Storage

Packagingper order / batch confirmation (not published)
Purityper batch COA (not published)
StorageSealed, cool and dry place
ShippingStandard chemical transport
SampleAvailable on request
Lead TimeIn stock / per order

Quality & Documentation

COA (Certificate of Analysis) is provided with every batch. MSDS/technical data sheets and third-party test reports are available on request. Purity and packaging are subject to batch COA and order confirmation.

Product Profile

Product Overview

Alendronic Acid is a carbon-based organic compound with CAS registry number 66376-36-1 and molecular formula C4H13NO7P2 (molecular weight 249.10), belonging to the organic chemicals segment of chemical raw materials.

Organic chemicals are the largest family of carbon-based compounds, widely used across pharmaceuticals, agrochemicals, materials, cosmetics and food industries.

Jinan Shenghe Chemical Co., Ltd. supplies Alendronic Acid with stable inventory and provides a Certificate of Analysis (COA) with each batch; custom repacking is available per process requirement.

Chemical Identity & Nomenclature

CAS number: 66376-36-1 — searchable in PubChem for physicochemical, safety and regulatory data.

Its molecular formula C4H13NO7P2 comprises 4 C, 13 H, 1 N, 7 O, 2 P atoms.

Also known as: Alendronic Acid

Category: organic chemicals

Applications & Use Cases

Downstream uses span pharmaceutical ingredients, agrochemicals, dyes, solvents, surfactants, food additives and polymer materials.

Specifications & Quality

Typical purity is per batch COA (not published). Packaging is per order / batch confirmation (not published). Storage: sealed, in a cool and dry place. Each batch ships with a COA; MSDS and other technical documents are available on request.

Sourcing & Support

Supplier: Jinan Shenghe Chemical Co., Ltd.. Samples can be arranged on request; lead time depends on stock and order size. Quotes are returned within one business day by email or WhatsApp.

Email: info@591daili.com · Tel/WhatsApp: +86-18553102138

Frequently Asked Questions

What is the CAS number of Alendronic Acid?

The CAS number of Alendronic Acid is 66376-36-1.

What purity and packaging are available?

Typical purity is per batch COA (not published), supplied in per order / batch confirmation (not published), with COA provided.

What are the applications of Alendronic Acid?

Main applications include Organic Chemicals.

What quality documents are provided?

Each batch ships with a Certificate of Analysis (COA). MSDS and other technical documents are available on request.

How should Alendronic Acid be stored and handled?

Store sealed in a cool, dry place. Handling and PPE follow the MSDS supplied with the batch; general chemical-handling precautions are recommended.

Can I request a sample?

Samples are available on request. Please contact us at info@591daili.com or via WhatsApp for details.

How do I buy Alendronic Acid or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Alendronic Acid · CAS 66376-36-1 · C4H13NO7P2. UNII X1J18R4W8P. Melting Point: 235; Melting Point: 233-235 °C (decomposes); Dissociation Constants: 2.72 (at 25 °C).

Identification

CAS Registry Number66376-36-1
PubChem CID2088
Molecular formulaC4H13NO7P2
IUPAC name(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
UNII (FDA)X1J18R4W8P

Computed Descriptors

Molecular Weight249.10
XLogP3-6.5
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass249.01672575
Monoisotopic Mass249.01672575
Topological Polar Surface Area161
Heavy Atom Count14
Formal Charge0

Physical & Chemical Properties

Melting Point235
Melting Point233-235 °C (decomposes)
Dissociation Constants2.72 (at 25 °C)

Physical description & handling notes

  • Solid
  • Fine white powder
  • MP: 257-262.5 °C. Soluble in water; very slightly soluble in alcohol. Practically insoluble in chloroform. /Alendronic acid, monosodium salt trihydrate/
  • pKa1 = 2.72; pKa2 = 8.73; pKa3 = 10.5; pKa4 = 11.6 (all at 25 °C)
  • Alendronic acid tablets have a very low oral bioavialability. After administration it distributes into soft tissue and bone or is excreted in the urine. Alendronic acid does not undergo metabolism.
  • Alendronate Sodium preparations: (AHFS, 2011)

Regulatory Status

GHS notification summary16.7% (1 / 6)

GHS Hazard Classification

GHS notification summary16.7% (1 / 6)
Reported hazard statementsH290 (16.7%), H302 (16.7%), H314 (66.7%), H315 (16.7%), H318 (16.7%), H319 (16.7%), H361 (16.7%), H371 (16.7%)

This chemical does not meet GHS hazard criteria for 16.7% (1 of 6) of reports.

H290 (16.7%): May be corrosive to metals [Warning Corrosive to Metals]

Documented Uses

  • Use (kg; approx.) in Germany (2009): >1000
  • Consumption (g per capita; approx.) in Germany (2009): 0.0122
  • Consumption (g per capita) in the USA (2002): 0.0155
  • For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.
  • Orthophosphorous acid is heated with 4-aminobutyric acid in an atmosphere of nitrogen and phosphorous trichloride is added to the melt. Finally, water is added, the solution is decolorized with charcoal, and diluted with methanol to precipitate the free acid which is treated with one equivalent of sodium hydroxide. /Alendronate sodium/
  • Alendronic acid is indicated for the treatment and prevention of osteoporosis in men and postmenopausal women, treatment of glucocorticoid-induced osteoporosis, and Paget's disease of bone. However, alendronic acid is not indicated for use in pediatric populations or patients with a creatinine clearance <35mL/min.

Synonyms

ALENDRONIC ACID; alendronate; 66376-36-1; (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid; Acido alendronico; Acide alendronique; Arendal; Acidum alendronicum; (4-Amino-1-hydroxybutylidene)bisphosphonic acid; ABDP; (4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid); 4-Amino-1-hydroxybutane-1,1-diphosphonic Acid; Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-; MK 217; X1J18R4W8P; 4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)

Frequently Asked Questions

What are the CAS number and molecular formula of Alendronic Acid?

CAS 66376-36-1; molecular formula C4H13NO7P2; molecular weight — g/mol.

What other names is Alendronic Acid known by?

ALENDRONIC ACID, alendronate, 66376-36-1, (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid, Acido alendronico, Acide alendronique.

Is Alendronic Acid classified as hazardous?

16.7% of GHS notifications report no hazard classification (1 of 6).

What are the key physical properties of Alendronic Acid?

Melting Point: 235; Melting Point: 233-235 °C (decomposes); Dissociation Constants: 2.72 (at 25 °C).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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