乙酰苯替丁

乙酰苯替丁（CAS 40674-52-0）：分子式 C10H13NO2、分子量 179.22。

产品概览

应用领域

登记用途：Uses: THERAP CAT: Analgesic、antipyretic、Former、US、THERAP CAT (VET): Analgesic、As stabilizer for hydrogen peroxide in hair bleaching prepn.、MEDICATION (VET)、MEDICATION、Used principally as an analgesic.、Use Classification: Cosmetics -> Stabilizing、Pharmaceuticals -> Animal Drugs -> Approved in Taiwan、Industry Uses: Not Known or Reasonably Ascertainable、Household Products: Cosmetics product ingredient: Phenacetin、Source: Phenacetin is made from other chemicals. Phenacetin was once used as a pain killer and fever reducer、but was removed from pharmaceuticals in 1983 by the U.S. Food and Drug Administration (FDA). Manufacturers sometimes add phenacetin to hair lighteners to stabilize chemicals in the product.、Potential health impacts: People may be exposed to phenacetin by ingestion. Studies of rats and mice given phenacetin showed increased rates of urinary tract tumors. Studies of rats given phenacetin also showed an increase in nasal cavity tumor. Studies of humans have shown phenacetin to increase rates of bladder and urinary tract cancer. The International Agency for Research on Cancer (IARC) categorizes phenacetin as a human carcinogen.、Product count: 33、Methods of Manufacturing: Condensation of p-nitrophenol in a sodium hydroxide solution with ethyl bromide followed by reduction with sodium sulfide and acetylation with acetic anhydride.、Obtained by reacting p-nitrophenol with sodium hydroxide & ethyl sulfate、reducing nitrite to amine with iron & acid、& then acetylating by boiling with glacial acetic acid.、By interaction of para-phenetidin & glacial acetic acid、or of ethyl bromide & para-acetaminophenol. Method of purification: crystallization.、Preparation: ... Eaker、Campbell、US 2887513 (1959 to Monsanto).、Impurities: ... Phenacetin is available in the US as a USP grade containing 98-101% active ingredient on a dried basis and a maximum of 0.03% para-chloracetanilide. In the European Pharmacopoeia ... specifications、sulphated ash is limited to 0.1%.、Formulations、Preparations: Grades: Technical、USP、as phenacetin.、Apcabuff contains 2.5 g phenacetin per tablet.、Pharmex Flu capsules contain 2.5 g phenacetin per tablet.、Phencaset contains 150 mg phenacetin per tablet.、For more Formulations、Preparations (Complete) data for PHENACETIN (6 total)、please visit the HSDB record page.、U.S. Production: 2022: 28、660 lb、2021: 71、154 lb、2020: 22、046 lb、(1976) PROBABLY GREATER THAN 4.54X10+5 GRAMS.、(1978) PROBABLY GREATER THAN 9.08X10+5 GRAMS、U.S. Imports: (1976) 2.32X10+8 GRAMS、(1978) 2.82X10+8 GRAMS (PRINCPL CUSTMS DISTS)、(1984) 3.75X10+7 g、General Manufacturing Information: All Other Basic Organic Chemical Manufacturing、Acetamide、N-(4-ethoxyphenyl)-: ACTIVE、Gives pasty mass with phenol、chloral hydrate or pyrocatechol、strong acids or alkalies、salicylic acid、oxidizers、iodine、spirit nitrous ether.、... Use of phenacetin by itself has been restricted to prescription in some countries.、Phenacetin has been employed only in analgesic mixtures. In recent years、it has been removed from almost all such mixtures. In some instances acetaminophen has been included to replace it.、A non-prostaglandin synthase inhibitor. It was utilized extensively in a wide variety of analgesic mixtures、but its causal role in analgesic-abuse nephropathy led to its withdrawal from the market. (From Smith and Reynard、Textbook of Pharmacology、1991、p431)、For more General Manufacturing Information (Complete) data for PHENACETIN (6 total)。

技术档案

这个产品是什么

乙酰苯替丁 是一种化工化合物，登记 CAS 号为 40674-52-0，分子式 C10H13NO2（分子量 179.22）。

识别信息

登记 CAS 号：40674-52-0

其分子式 C10H13NO2 由 10 个碳、13 个氢、1 个氮、2 个氧 组成。

别名/同义词：乙酰苯替丁 · Acetophenetidine

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PubChem 公开数据