Acetamide (CAS 60-35-5) — formula C2H5NO, molecular weight 59.07.
| CAS Number | 60-35-5 |
|---|---|
| Molecular Formula | C2H5NO |
| Molecular Weight | 59.07 |
| Melting Point | 180.1 °F (NTP, 1992) |
| Boiling Point | 430 °F at 760 mmHg (NTP, 1992) |
| LogP | -0.9 |
| Applications | Uses: Acetamide is used as a solvent, plasticizer, and a wetting and penetrating agent., Used as a solvent, stabilizer, humectant for paper, hygroscopic agent, wetting agent, penetrating agent, and denaturant of alcohol, Also used in lacquers, explosives, and soldering fluxes, [HSDB] Used as a solvent in the following applications: plasticizers, lacquers, soldering flux, wetting agents, and synthesis of other agents, [ACGIH], Soldering [Category: Heat or Machine], Pulp and Paper Processing [Category: Industry], Painting (Solvents) [Category: Paint], Solvent, molten acetamide is an excellent solvent for many organic and inorganic compounds. Solubilizer, renders sparingly soluble substances more soluble in water by mere addition or by fusion. Plasticizer, stabilizer. Manufacture of methylamine, denaturing alcohol. In organic synthesis., Organic synthesis (reactant, solvent, peroxide stabilizer), general solvent, penetrating agent., It suppresses acid buildup in printing inks, and perfumes. It is a mild moisturizer and is used as a softener for leather, textiles, paper, and certain plastics. ... Acetamide and substituted acetamide-containing thiourea can be used for treatment of herpes viruses. Derivatives can also be used as feeding behavior modifiers., MEDICATION, This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation., Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Methods of Manufacturing: Prepared by fractional distillation of ammonium acetate., Interaction of ethyl acetate and ammonium hydroxide., Acetamide can be produced by several methods. Ammonia reacts vigorously with acetyl halides or acetic anhydride to produce acetamide. Alkyl acetates also react with ammonia to yield acetamide. Dehydration of ammonium acetate is the standard procedure for preparation of acetamide. Finally, acetonitrile is hydrolyzed to yield acetamide in the presence of an acid or base catalyst., Formulations, Preparations: In 1963 ... available in USA as technical grade (99% minimum acetamide and 0.3% maximum free acid) and as chemically pure, odorless grade (99.5-99.9% acetamide and trace of free acid)., Grades: Technical, CP, chemically pure: a grade designation signifying a minimum of impurities, but not 100% purity, (odorless), intermediate, reagent., General Manufacturing Information: Acetamide: ACTIVE |
Documented applications: Uses: Acetamide is used as a solvent, plasticizer, and a wetting and penetrating agent., Used as a solvent, stabilizer, humectant for paper, hygroscopic agent, wetting agent, penetrating agent, and denaturant of alcohol, Also used in lacquers, explosives, and soldering fluxes, [HSDB] Used as a solvent in the following applications: plasticizers, lacquers, soldering flux, wetting agents, and synthesis of other agents, [ACGIH], Soldering [Category: Heat or Machine], Pulp and Paper Processing [Category: Industry], Painting (Solvents) [Category: Paint], Solvent, molten acetamide is an excellent solvent for many organic and inorganic compounds. Solubilizer, renders sparingly soluble substances more soluble in water by mere addition or by fusion. Plasticizer, stabilizer. Manufacture of methylamine, denaturing alcohol. In organic synthesis., Organic synthesis (reactant, solvent, peroxide stabilizer), general solvent, penetrating agent., It suppresses acid buildup in printing inks, and perfumes. It is a mild moisturizer and is used as a softener for leather, textiles, paper, and certain plastics. ... Acetamide and substituted acetamide-containing thiourea can be used for treatment of herpes viruses. Derivatives can also be used as feeding behavior modifiers., MEDICATION, This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation., Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Methods of Manufacturing: Prepared by fractional distillation of ammonium acetate., Interaction of ethyl acetate and ammonium hydroxide., Acetamide can be produced by several methods. Ammonia reacts vigorously with acetyl halides or acetic anhydride to produce acetamide. Alkyl acetates also react with ammonia to yield acetamide. Dehydration of ammonium acetate is the standard procedure for preparation of acetamide. Finally, acetonitrile is hydrolyzed to yield acetamide in the presence of an acid or base catalyst., Formulations, Preparations: In 1963 ... available in USA as technical grade (99% minimum acetamide and 0.3% maximum free acid) and as chemically pure, odorless grade (99.5-99.9% acetamide and trace of free acid)., Grades: Technical, CP, chemically pure: a grade designation signifying a minimum of impurities, but not 100% purity, (odorless), intermediate, reagent., General Manufacturing Information: Acetamide: ACTIVE.
Acetamide is a chemical compound with CAS registry number 60-35-5 and molecular formula C2H5NO (molecular weight 59.07).
CAS number: 60-35-5
Its molecular formula C2H5NO comprises 2 C, 5 H, 1 N, 1 O atoms.
Also known as: Acetamide · 乙酰胺 · Acetamide Reagent
The CAS registry number of Acetamide is 60-35-5.
Molecular formula C2H5NO, molecular weight 59.07.
It is also registered under: Acetamide, 乙酰胺, Acetamide Reagent.
Recorded applications: Uses: Acetamide is used as a solvent, plasticizer, and a wetting and penetrating agent., Used as a solvent, stabilizer, humectant for paper, hygroscopic agent, wetting agent, penetrating agent, and denaturant of alcohol, Also used in lacquers, explosives, and soldering fluxes, [HSDB] Used as a solvent in the following applications: plasticizers, lacquers, soldering flux, wetting agents, and synthesis of other agents, [ACGIH], Soldering [Category: Heat or Machine], Pulp and Paper Processing [Category: Industry], Painting (Solvents) [Category: Paint], Solvent, molten acetamide is an excellent solvent for many organic and inorganic compounds. Solubilizer, renders sparingly soluble substances more soluble in water by mere addition or by fusion. Plasticizer, stabilizer. Manufacture of methylamine, denaturing alcohol. In organic synthesis., Organic synthesis (reactant, solvent, peroxide stabilizer), general solvent, penetrating agent., It suppresses acid buildup in printing inks, and perfumes. It is a mild moisturizer and is used as a softener for leather, textiles, paper, and certain plastics. ... Acetamide and substituted acetamide-containing thiourea can be used for treatment of herpes viruses. Derivatives can also be used as feeding behavior modifiers., MEDICATION, This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation., Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Methods of Manufacturing: Prepared by fractional distillation of ammonium acetate., Interaction of ethyl acetate and ammonium hydroxide., Acetamide can be produced by several methods. Ammonia reacts vigorously with acetyl halides or acetic anhydride to produce acetamide. Alkyl acetates also react with ammonia to yield acetamide. Dehydration of ammonium acetate is the standard procedure for preparation of acetamide. Finally, acetonitrile is hydrolyzed to yield acetamide in the presence of an acid or base catalyst., Formulations, Preparations: In 1963 ... available in USA as technical grade (99% minimum acetamide and 0.3% maximum free acid) and as chemically pure, odorless grade (99.5-99.9% acetamide and trace of free acid)., Grades: Technical, CP, chemically pure: a grade designation signifying a minimum of impurities, but not 100% purity, (odorless), intermediate, reagent., General Manufacturing Information: Acetamide: ACTIVE.
Independent reference data for Acetamide (CAS 60-35-5), compiled from public chemistry databases.
| CAS Registry Number | 60-35-5 |
|---|---|
| PubChem CID | 178 |
| Molecular formula | C2H5NO |
| IUPAC name | acetamide |
| UNII (FDA) | 8XOE1JSO29 |
| JECFA number | 1592 |
| Molecular Weight | 59.07 |
|---|---|
| XLogP3 | -0.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 59.037113783 |
| Monoisotopic Mass | 59.037113783 |
| Topological Polar Surface Area | 43.1 |
| Heavy Atom Count | 4 |
| Boiling Point | 430 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 222 |
| Boiling Point | 222 °C at 760 mm Hg |
| Boiling Point | 221.00 to 222.00 °C. @ 760.00 mm Hg |
| Boiling Point | 222 °C |
| Boiling Point | 430 °F |
| Boiling Point | 221 °C @760 [mm Hg] |
| Melting Point | 180.1 °F (NTP, 1992) |
| Melting Point | 81 |
| Melting Point | 81.16 °C |
acetamide; 60-35-5; Ethanamide; Acetic acid amide; Methanecarboxamide; Acetimidic acid; Ethanimidic acid; Amid kyseliny octove; NCI-C02108; CH3CONH2; DTXSID7020005; AI3-02060; 8XOE1JSO29; NSC 25945; NSC-25945; DTXCID505
| Regulatory & Food Contact | FDA Substance added to food: FLAVORING AGENT OR ADJUVANT FLAVOURING_AGENT: Flavouring Agent ACETAMIDE--NLFG TRS 934-JECFA 65/89 FAS 56-JECFA 65 |
|---|
| Reported hazard statements | H351, H361, H320, H316 |
|---|
H351: Suspected of causing cancer [Warning Carcinogenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
Acetamide Reagent · CAS 60-35-5 · C2H5NO. UNII 8XOE1JSO29. Boiling Point: 430 °F at 760 mmHg (NTP, 1992); Boiling Point: 222; Boiling Point: 222 °C at 760 mm Hg.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 乙酰胺