Acalabrutinib (CAS 1420477-60-6) — formula C26H23N7O2, molecular weight 465.5; category pharmaceutical intermediates and APIs.
Acalabrutinib (CAS 1420477-60-6) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C26H23N7O2 comprises 26 C, 23 H, 7 N, 2 O atoms. Its molecular weight is about 465.5. Reported physicochemical data: LogP about 0.49. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 1420477-60-6 |
|---|---|
| Molecular Formula | C26H23N7O2 |
| Molecular Weight | 465.5 |
| LogP | 0.49 |
| Category | Pharmaceutical Intermediates & APIs |
Acalabrutinib is a pharmaceutical intermediate or API compound with CAS registry number 1420477-60-6 and molecular formula C26H23N7O2 (molecular weight 465.5), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 1420477-60-6
Its molecular formula C26H23N7O2 comprises 26 C, 23 H, 7 N, 2 O atoms.
Also known as: Acalabrutinib · 阿卡拉布替尼
Category: pharmaceutical intermediates and APIs
The CAS registry number of Acalabrutinib is 1420477-60-6.
Molecular formula C26H23N7O2, molecular weight 465.5.
It is also registered under: Acalabrutinib, 阿卡拉布替尼.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Acalabrutinib (CAS 1420477-60-6), compiled from public chemistry databases.
| CAS Registry Number | 1420477-60-6 |
|---|---|
| PubChem CID | 71226662 |
| Molecular formula | C26H23N7O2 |
| IUPAC name | 4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide |
| UNII (FDA) | I42748ELQW |
| Molecular Weight | 465.5 |
|---|---|
| XLogP3 | 3 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 4 |
| Exact Mass | 465.19132300 |
| Monoisotopic Mass | 465.19132300 |
| Topological Polar Surface Area | 119 |
| Heavy Atom Count | 35 |
| LogP | 0.49 |
|---|
Acalabrutinib; 1420477-60-6; ACP-196; acalabrutinibum; 4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide; I42748ELQW; CHEBI:167707; DTXSID401026209; 4-[8-Amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide; 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide; 4-(8-Amino-3-((2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl)imidazo(1,5-a)pyrazin-1-yl)-N-2-pyridinylbenzamide; 4-(8-amino-3-((2S)-1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo(1,5-a)pyrazin-1-yl)-N-(pyridin-2-yl)benzamide; 4-(8-amino-3-((2S)-1-but-2-ynoylpyrrolidin-2-yl)imidazo(1,5-a)pyrazin-1-yl)-N-pyridin-2-ylbenzamide; RefChem:57414; L01XE51; DTXCID401510462
| GHS notification summary | 33.3% (1 / 3) |
|---|
| GHS notification summary | 33.3% (1 / 3) |
|---|---|
| Reported hazard statements | H373 (66.7%) |
This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.
H373 (66.7%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
Acalabrutinib · CAS 1420477-60-6 · C26H23N7O2. UNII I42748ELQW. LogP: 0.49.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 阿卡拉布替尼