6A-methyl-11B-hydroxyprogesterone

Description

6A-methyl-11B-hydroxyprogesterone · CAS 2668-66-8 · C22H32O3. UNII D2UFC189XF. Melting Point: 156.5; Melting Point: 156.5 °C; Solubility: 3.37e-02 g/L.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Solid
• 183.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 207.51 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 177.09 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 182.09 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Documented Uses

• For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity.
• A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
• Established Pharmacologic Class [EPC] - Corticosteroid
• Mechanisms of Action [MoA] - Corticosteroid Hormone Receptor Agonists
• Medrysone is a Corticosteroid. The mechanism of action of medrysone is as a Corticosteroid Hormone Receptor Agonist.
• QS01B - Antiinflammatory agents

Synonyms

medrysone; 2668-66-8; Hydroxymesterone; U-8471; NSC-63278; 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione; DTXSID6045371; D2UFC189XF; 6-alpha-Methyl-11-beta-hydroxyprogesterone; DTXCID4025371; NSC63278; 11-beta-Hydroxy-6-alpha-methylpregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 11-hydroxy-6-methyl-, (6alpha,11beta)-; HMS suspension; RefChem:55563; 11-hydroxy-6-methylprogesterone

Frequently Asked Questions

What are the CAS number and molecular formula of 6A-methyl-11B-hydroxyprogesterone?

CAS 2668-66-8; molecular formula C22H32O3; molecular weight — g/mol.

What other names is 6A-methyl-11B-hydroxyprogesterone known by?

medrysone, 2668-66-8, Hydroxymesterone, U-8471, NSC-63278, 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione.

What are the key physical properties of 6A-methyl-11B-hydroxyprogesterone?

Melting Point: 156.5; Melting Point: 156.5 °C; Solubility: 3.37e-02 g/L; LogP: 3.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.