5-Hydroxymethyl-2-furaldehyde (CAS 67-47-0) — formula C6H6O3, molecular weight 126.11.
| CAS Number | 67-47-0 |
|---|---|
| Molecular Formula | C6H6O3 |
| Molecular Weight | 126.11 |
| Melting Point | 31.5 °C |
| Boiling Point | BP: 115 °C at 1 mm Hg |
| LogP | -0.6 |
| Applications | Uses: Used to make dialdehydes, glycols, ethers, aminoalcohols, and acetals, [Merck Index] A flavoring agent that naturally occurs in some foods and alcoholic beverages, [ExPub: EFSA] Renewable building block for organic syntheses. [HSDB] Formed when sugars such as fructose or glucose are heated in the presence of amino acids, and is ubiquitous in the diet, Also used to make phenol, furfural resins, [NTP], In the synthesis of dialdehydes, amino alcohols, acetals. Aqueous acid catalyzes ring opening., Formation of 5-hydroxymethyl-2-furfuraldehyde can be used as an index of excessive heat treatment and of deteriorative changes in food, Formation of 5-hydroxymethyl-2-furfuraldehyde can be used as an index of excessive heat treatment and of deteriorative changes in honey., Renewable building block for organic syntheses, Methods of Manufacturing: The acid-catalyzed dehydration of hexoses results in the formation of 5-hydroxymethylfurfural (HMF). Fructose and insulin are especially good starting materials., ... From fructose or inulin hydrolysates by acid-induced elimination of three molecular equivalents of water., Prepared from the fructose portion of the sugar molecule in 57% yield, From glucose, cornstarch, sucrose, molasses, For more Methods of Manufacturing (Complete) data for 5-Hydroxymethyl-2-furfuraldehyde (6 total), please visit the HSDB record page., General Manufacturing Information: 2-Furancarboxaldehyde, 5-(hydroxymethyl)-: ACTIVE, In acid solution, either after standing for a prolonged time or after heating, dextrose undergoes polycondensation, ie, dehydration, yielding a mixture of di- and oligosaccharides, most of which are the disaccharides gentiobiose and isomaltose. In acid solution and at high temperature, dehydration leads to formation of 5-hydroxymethyl-2-furfuraldehyde. |
Documented applications: Uses: Used to make dialdehydes, glycols, ethers, aminoalcohols, and acetals, [Merck Index] A flavoring agent that naturally occurs in some foods and alcoholic beverages, [ExPub: EFSA] Renewable building block for organic syntheses. [HSDB] Formed when sugars such as fructose or glucose are heated in the presence of amino acids, and is ubiquitous in the diet, Also used to make phenol, furfural resins, [NTP], In the synthesis of dialdehydes, amino alcohols, acetals. Aqueous acid catalyzes ring opening., Formation of 5-hydroxymethyl-2-furfuraldehyde can be used as an index of excessive heat treatment and of deteriorative changes in food, Formation of 5-hydroxymethyl-2-furfuraldehyde can be used as an index of excessive heat treatment and of deteriorative changes in honey., Renewable building block for organic syntheses, Methods of Manufacturing: The acid-catalyzed dehydration of hexoses results in the formation of 5-hydroxymethylfurfural (HMF). Fructose and insulin are especially good starting materials., ... From fructose or inulin hydrolysates by acid-induced elimination of three molecular equivalents of water., Prepared from the fructose portion of the sugar molecule in 57% yield, From glucose, cornstarch, sucrose, molasses, For more Methods of Manufacturing (Complete) data for 5-Hydroxymethyl-2-furfuraldehyde (6 total), please visit the HSDB record page., General Manufacturing Information: 2-Furancarboxaldehyde, 5-(hydroxymethyl)-: ACTIVE, In acid solution, either after standing for a prolonged time or after heating, dextrose undergoes polycondensation, ie, dehydration, yielding a mixture of di- and oligosaccharides, most of which are the disaccharides gentiobiose and isomaltose. In acid solution and at high temperature, dehydration leads to formation of 5-hydroxymethyl-2-furfuraldehyde..
5-Hydroxymethyl-2-furaldehyde is a chemical compound with CAS registry number 67-47-0 and molecular formula C6H6O3 (molecular weight 126.11).
CAS number: 67-47-0
Its molecular formula C6H6O3 comprises 6 C, 6 H, 3 O atoms.
Also known as: 5-Hydroxymethyl-2-furaldehyde · 5-羟甲基-2-糠醛 · 5-Hydroxymethylfurfural
The CAS registry number of 5-Hydroxymethyl-2-furaldehyde is 67-47-0.
Molecular formula C6H6O3, molecular weight 126.11.
It is also registered under: 5-Hydroxymethyl-2-furaldehyde, 5-羟甲基-2-糠醛, 5-Hydroxymethylfurfural.
Recorded applications: Uses: Used to make dialdehydes, glycols, ethers, aminoalcohols, and acetals, [Merck Index] A flavoring agent that naturally occurs in some foods and alcoholic beverages, [ExPub: EFSA] Renewable building block for organic syntheses. [HSDB] Formed when sugars such as fructose or glucose are heated in the presence of amino acids, and is ubiquitous in the diet, Also used to make phenol, furfural resins, [NTP], In the synthesis of dialdehydes, amino alcohols, acetals. Aqueous acid catalyzes ring opening., Formation of 5-hydroxymethyl-2-furfuraldehyde can be used as an index of excessive heat treatment and of deteriorative changes in food, Formation of 5-hydroxymethyl-2-furfuraldehyde can be used as an index of excessive heat treatment and of deteriorative changes in honey., Renewable building block for organic syntheses, Methods of Manufacturing: The acid-catalyzed dehydration of hexoses results in the formation of 5-hydroxymethylfurfural (HMF). Fructose and insulin are especially good starting materials., ... From fructose or inulin hydrolysates by acid-induced elimination of three molecular equivalents of water., Prepared from the fructose portion of the sugar molecule in 57% yield, From glucose, cornstarch, sucrose, molasses, For more Methods of Manufacturing (Complete) data for 5-Hydroxymethyl-2-furfuraldehyde (6 total), please visit the HSDB record page., General Manufacturing Information: 2-Furancarboxaldehyde, 5-(hydroxymethyl)-: ACTIVE, In acid solution, either after standing for a prolonged time or after heating, dextrose undergoes polycondensation, ie, dehydration, yielding a mixture of di- and oligosaccharides, most of which are the disaccharides gentiobiose and isomaltose. In acid solution and at high temperature, dehydration leads to formation of 5-hydroxymethyl-2-furfuraldehyde..
Independent reference data for 5-Hydroxymethyl-2-furaldehyde (CAS 67-47-0), compiled from public chemistry databases.
| CAS Registry Number | 67-47-0 |
|---|---|
| PubChem CID | 237332 |
| Molecular formula | C6H6O3 |
| IUPAC name | 5-(hydroxymethyl)furan-2-carbaldehyde |
| UNII (FDA) | 70ETD81LF0 |
| Molecular Weight | 126.11 |
|---|---|
| XLogP3 | -0.6 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 126.031694049 |
| Monoisotopic Mass | 126.031694049 |
| Topological Polar Surface Area | 50.4 |
| Heavy Atom Count | 9 |
| Boiling Point | BP: 115 °C at 1 mm Hg |
|---|---|
| Boiling Point | 114.00 to 116.00 °C. @ 1.00 mm Hg |
| Melting Point | 31.5 °C |
| Melting Point | 35 - 35.5 °C |
| Density | 1.2062 g/cu cm at 25 °C |
| Vapor Pressure | 0.00528 [mmHg] |
5-HYDROXYMETHYLFURFURAL; 67-47-0; 5-Hydroxymethyl-2-furaldehyde; 5-(Hydroxymethyl)furfural; 5-(Hydroxymethyl)-2-furaldehyde; 5-Oxymethylfurfurole; Hydroxymethylfurfurole; Hydroxymethylfurfuraldehyde; 5-(Hydroxymethyl)-2-furancarbonal; 2-Furancarboxaldehyde, 5-(hydroxymethyl)-; 5-Hydroxymethylfuran-2-aldehyde; 5-Hydroxymethyl-2-formylfuran; Hydroxymethylfurfuralaldehyde; 2-Hydroxymethyl-5-furfural; 5-hydroxymethyl furfural; 5-(Hydroxymethyl)-2-furfuraldehyde
| Regulatory & Food Contact | EU Flavoring substances Flavoring Agents |
|---|---|
| GHS notification summary | 1.2% (4 / 344) |
| GHS notification summary | 1.2% (4 / 344) |
|---|---|
| Reported hazard statements | H315 (60.2%), H319 (65.1%), H335 (64.2%), H412 (70.9%) |
This chemical does not meet GHS hazard criteria for 1.2% (4 of 344) of reports.
H315 (60.2%): Causes skin irritation [Warning Skin corrosion/irritation]
5-Hydroxymethylfurfural · CAS 67-47-0 · C6H6O3. UNII 70ETD81LF0. Boiling Point: BP: 115 °C at 1 mm Hg; Boiling Point: 114.00 to 116.00 °C. @ 1.00 mm Hg; Melting Point: 31.5 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 5-羟甲基-2-糠醛