4-Hydroxy-3-methoxybenzaldehyde (CAS 121-33-5) — formula C8H8O3, molecular weight 152.15; category pharmaceutical intermediates and APIs.
4-Hydroxy-3-methoxybenzaldehyde (CAS 121-33-5) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C8H8O3 comprises 8 C, 8 H, 3 O atoms. Its molecular weight is about 152.15. Reported physicochemical data: melting point around 178 to 181 °F (NTP, 1992), boiling point around 545 °F at 760 mmHg (NTP, 1992), LogP about 1.2. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 121-33-5 |
|---|---|
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 |
| Melting Point | 178 to 181 °F (NTP, 1992) |
| Boiling Point | 545 °F at 760 mmHg (NTP, 1992) |
| LogP | 1.2 |
| Applications | Flavoring and nutrient, Fragrance, Fragrance Ingredients, Masking |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: Flavoring and nutrient, Fragrance, Fragrance Ingredients, Masking.
4-Hydroxy-3-methoxybenzaldehyde is a pharmaceutical intermediate or API compound with CAS registry number 121-33-5 and molecular formula C8H8O3 (molecular weight 152.15), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 121-33-5
Its molecular formula C8H8O3 comprises 8 C, 8 H, 3 O atoms.
Also known as: 4-Hydroxy-3-methoxybenzaldehyde · Vanillin · Vanilla
Category: pharmaceutical intermediates and APIs
The CAS registry number of 4-Hydroxy-3-methoxybenzaldehyde is 121-33-5.
Molecular formula C8H8O3, molecular weight 152.15.
It is also registered under: 4-Hydroxy-3-methoxybenzaldehyde, Vanillin, Vanilla.
Recorded applications: Flavoring and nutrient, Fragrance, Fragrance Ingredients, Masking.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for 4-Hydroxy-3-methoxybenzaldehyde (CAS 121-33-5), compiled from public chemistry databases.
| CAS Registry Number | 121-33-5 |
|---|---|
| PubChem CID | 1183 |
| Molecular formula | C8H8O3 |
| IUPAC name | 4-hydroxy-3-methoxybenzaldehyde |
| UNII (FDA) | CHI530446X |
| FEMA number | 3107 |
| JECFA number | 889 |
| Molecular Weight | 152.15 |
|---|---|
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 152.047344113 |
| Monoisotopic Mass | 152.047344113 |
| Topological Polar Surface Area | 46.5 |
| Heavy Atom Count | 11 |
| Boiling Point | 545 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 285 °C |
| Boiling Point | 285.00 to 286.00 °C. @ 760.00 mm Hg |
| Melting Point | 178 to 181 °F (NTP, 1992) |
| Melting Point | 81-83 °C |
| Melting Point | 81.5 °C |
| Flash Point | 153 °C (307 °F) - closed cup |
| Flash Point | 153 °C c.c. |
| Solubility | In water, 1.102X10+4 mg/L at 25 °C |
| Solubility | 11 mg/mL at 25 °C |
vanillin; 4-Hydroxy-3-methoxybenzaldehyde; 121-33-5; Vanillic aldehyde; Vanillaldehyde; p-Vanillin; Vanilline; Lioxin; 3-Methoxy-4-hydroxybenzaldehyde; 4-Hydroxy-3-methoxy-benzaldehyde; Benzaldehyde, 4-hydroxy-3-methoxy-; 4-Hydroxy-m-anisaldehyde; 2-Methoxy-4-formylphenol; Zimco; p-Hydroxy-m-methoxybenzaldehyde; 4-Formyl-2-methoxyphenol
| Regulatory & Food Contact | EU Flavoring substances FDA Substance added to food: COLOR OR COLORING ADJUNCT, FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Vanilla Scientific procedures |
|---|---|
| GHS notification summary | 1.8% (42 / 2387) |
| GHS notification summary | 1.8% (42 / 2387) |
|---|---|
| Reported hazard statements | H317 (14.3%), H319 (83.5%), H302 (100%), H411 (100%), H320, H402, H412 |
This chemical does not meet GHS hazard criteria for 1.8% (42 of 2387) of reports.
H317 (14.3%): May cause an allergic skin reaction [Warning Sensitization, Skin]
4-Hydroxy-3-methoxybenzaldehyde · CAS 121-33-5 · C8H8O3. UNII CHI530446X. Boiling Point: 545 °F at 760 mmHg (NTP, 1992); Boiling Point: 285 °C; Boiling Point: 285.00 to 286.00 °C. @ 760.00 mm Hg.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.