3-Chloropyridine

Description

3-Chloropyridine · CAS 6266-00-8 · C5H4ClN. UNII 1M13HUC1P4. Boiling Point: 151 °C; Boiling Point: BP: 85-87 °C at 100 mm Hg; Flash Point: 66 °C (151 °F) - closed cup.

Identification

CAS Registry Number	6266-00-8
PubChem CID	12287
Molecular formula	C5H4ClN
IUPAC name	3-chloropyridine
UNII (FDA)	1M13HUC1P4

Computed Descriptors

Molecular Weight	113.54
XLogP3	1.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	113.0032268
Monoisotopic Mass	113.0032268
Topological Polar Surface Area	12.9
Heavy Atom Count	7
Formal Charge	0

Physical & Chemical Properties

Boiling Point	151 °C
Boiling Point	BP: 85-87 °C at 100 mm Hg
Flash Point	66 °C (151 °F) - closed cup
Vapor Pressure	4.0 [mmHg]
LogP	log Kow = 1.33
LogP	1.33
Ionization Efficiency	2.7
Ionization Efficiency	MeCN (80%)
Ionization Efficiency	DOI:10.1021/ac902856t

Physical description & handling notes

• Clear, colorless to light yellow liquid;
• Clear liquid
• Slightly soluble in water
• Stable under recommended storage conditions.
• When heated to decomposition it emits very toxic fumes of /chloride and nitrogen oxides/.
• Positive

GHS Hazard Classification

Reported hazard statements	H226 (12%), H302 (92%), H312 (82%), H315 (16%), H332 (82%), H227, H310, H318

Documented Uses

• Laboratory chemicals, synthesis of substances.
• Pyrroles may be ring-expanded to pyridines in reactions having a greater academic than practical interest. Treatment of pyrrole with chloroform and sodium ethoxide (in effect, with dichlorocarbene,: CCl2) gives a low yield of 3-chloropyridine. Amuch better yield (33%) is obtained if chloroform and pyrrole are heated together in the vapor phase at 550 °C; some 2-chloropyridine is also formed.

Synonyms

3-CHLOROPYRIDINE; Pyridine, 3-chloro-; m-Chloropyridine; 3-chloro pyridine; 3-pyridinyl chloride; .beta.-Chloropyridine; EINECS 210-955-7; NSC 60200; CCRIS 1715; DTXSID3052309; UNII-1M13HUC1P4; NSC-60200; BRN 0105744; 1M13HUC1P4; DTXCID4030881; HSDB 8485

Frequently Asked Questions

What are the CAS number and molecular formula of 3-Chloropyridine?

CAS 6266-00-8; molecular formula C5H4ClN; molecular weight — g/mol.

What other names is 3-Chloropyridine known by?

3-CHLOROPYRIDINE, Pyridine, 3-chloro-, m-Chloropyridine, 3-chloro pyridine, 3-pyridinyl chloride, .beta.-Chloropyridine.

Is 3-Chloropyridine classified as hazardous?

Hazard statements reported: H226, H302, H312, H315, H332.

What are the key physical properties of 3-Chloropyridine?

Boiling Point: 151 °C; Boiling Point: BP: 85-87 °C at 100 mm Hg; Flash Point: 66 °C (151 °F) - closed cup; Vapor Pressure: 4.0 [mmHg].

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.