3,5-二甲基-1-氨基金刚烷（CAS 19982-08-2）：分子式 C12H21N、分子量 179.30。
| CAS号 | 19982-08-2 |
|---|---|
| 分子式 | C12H21N |
| 分子量 | 179.30 |
| 熔点 | 153 |
| 沸点 | 239.8 |
| LogP | 3.28 |
| 应用领域 | Uses: MEDICATION、MEDICATION (VET)、Antiparkinson Agents、Dopamine Agents、Excitatory Amino Acid Antagonists、Use (kg、approx.) in Germany (2009): >500、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Calculated removal (%): 61.6、For the treatment of moderate to severe dementia of the Alzheimer's type.、Use Classification: Pharmaceuticals、Methods of Manufacturing:、Preparation、of the free base and hydrochloride: J. Mills、E. Krumkalns、USA 3391142 (1968 to Lilly).、Formulations、Preparations: Table: Memantine Hydrochloride Preparations [Table#6915]、General Manufacturing Information: NMDA-receptor antagonist、derivative of adamantane.、Information available in 2005 indicated that Memantine hydrochloride was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Belgium、Colombia、Denmark、Dominican Republic、El Salvador、Finland、France、Germany、Guatemala、Honduras、Hungary、Ireland、Luxembourg、Norway、Panama、Russian Federation、Spain、Switzerland、United Kingdom、United States (1、2) |
登记用途：Uses: MEDICATION、MEDICATION (VET)、Antiparkinson Agents、Dopamine Agents、Excitatory Amino Acid Antagonists、Use (kg、approx.) in Germany (2009): >500、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Calculated removal (%): 61.6、For the treatment of moderate to severe dementia of the Alzheimer's type.、Use Classification: Pharmaceuticals、Methods of Manufacturing:、Preparation、of the free base and hydrochloride: J. Mills、E. Krumkalns、USA 3391142 (1968 to Lilly).、Formulations、Preparations: Table: Memantine Hydrochloride Preparations [Table#6915]、General Manufacturing Information: NMDA-receptor antagonist、derivative of adamantane.、Information available in 2005 indicated that Memantine hydrochloride was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Belgium、Colombia、Denmark、Dominican Republic、El Salvador、Finland、France、Germany、Guatemala、Honduras、Hungary、Ireland、Luxembourg、Norway、Panama、Russian Federation、Spain、Switzerland、United Kingdom、United States (1、2)。
3,5-二甲基-1-氨基金刚烷 是一种化工化合物，登记 CAS 号为 19982-08-2，分子式 C12H21N（分子量 179.30）。
登记 CAS 号：19982-08-2
其分子式 C12H21N 由 12 个碳、21 个氢、1 个氮 组成。
别名/同义词：3,5-二甲基-1-氨基金刚烷 · 3,5-Dimethyl-1-aminoadamantane
3,5-二甲基-1-氨基金刚烷 的 CAS 登记号为 19982-08-2。
分子式 C12H21N，分子量 179.30。
别名/同义词：3,5-二甲基-1-氨基金刚烷、3,5-Dimethyl-1-aminoadamantane。
登记用途：Uses: MEDICATION、MEDICATION (VET)、Antiparkinson Agents、Dopamine Agents、Excitatory Amino Acid Antagonists、Use (kg、approx.) in Germany (2009): >500、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Calculated removal (%): 61.6、For the treatment of moderate to severe dementia of the Alzheimer's type.、Use Classification: Pharmaceuticals、Methods of Manufacturing:、Preparation、of the free base and hydrochloride: J. Mills、E. Krumkalns、USA 3391142 (1968 to Lilly).、Formulations、Preparations: Table: Memantine Hydrochloride Preparations [Table#6915]、General Manufacturing Information: NMDA-receptor antagonist、derivative of adamantane.、Information available in 2005 indicated that Memantine hydrochloride was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Belgium、Colombia、Denmark、Dominican Republic、El Salvador、Finland、France、Germany、Guatemala、Honduras、Hungary、Ireland、Luxembourg、Norway、Panama、Russian Federation、Spain、Switzerland、United Kingdom、United States (1、2)。
3,5-二甲基-1-氨基金刚烷（CAS 19982-08-2）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 19982-08-2 |
|---|---|
| PubChem CID | 4054 |
| Molecular formula | C12H21N |
| IUPAC name | 3,5-dimethyladamantan-1-amine |
| UNII (FDA) | W8O17SJF3T |
| Molecular Weight | 179.30 |
|---|---|
| XLogP3 | 3.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 179.167399674 |
| Monoisotopic Mass | 179.167399674 |
| Topological Polar Surface Area | 26 |
| Heavy Atom Count | 13 |
| Boiling Point | 239.8 |
|---|---|
| Melting Point | 153 |
| Solubility | 4.55e-02 g/L |
| LogP | 3.28 |
| LogP | log Kow = 3.28 |
| LogP | 3.5 |
| Dissociation Constants | 10.27 |
memantine; 19982-08-2; 3,5-dimethyladamantan-1-amine; 1-Amino-3,5-dimethyladamantane; Memantina; 3,5-Dimethyl-1-adamantanamine; Memantinum; 1,3-Dimethyl-5-adamantanamine; nemdatine; 3,5-Dimethyl-1-aminoadamantane; Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimethyl-; DTXSID5045174; DRG-0267; 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine; W8O17SJF3T; D-145
| GHS notification summary | 50% (1 / 2) |
|---|
| GHS notification summary | 50% (1 / 2) |
|---|---|
| Reported hazard statements | H302 (50%) |
This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
3,5-Dimethyl-1-aminoadamantane · CAS 19982-08-2 · C12H21N. UNII W8O17SJF3T. Boiling Point: 239.8; Melting Point: 153; Solubility: 4.55e-02 g/L.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: 3,5-Dimethyl-1-aminoadamantane