2-Bromo-2-nitro-1,3-propanediol

Independent reference data for 2-Bromo-2-nitro-1,3-propanediol (CAS 52-51-7), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

CIR ingredient: 2-Bromo-2-Nitropropane-1,3-DiolBronopol is a preservative and antiseptic used in cosmetics and topical medications. It is used as a preservative in paints, textiles, cooling towers, humidifiers, and hide processing. [Marks, p. 136-7] Used in cleaning agents, paints, cosmetics, glues, paper mills, water systems, metalworking fluids, polishes, and printing inks; [Kanerva, p. 405]

Synonyms and trade names

bronopol; 52-51-7; 2-Bromo-2-nitro-1,3-propanediol; 2-Bromo-2-nitropropane-1,3-diol; Bronosol; Bronocot; Bronotak; Bronidiol; Bronopolu; Lexgard bronopol; Onyxide 500; Bronopolum; 1,3-Propanediol, 2-bromo-2-nitro-; 2-Nitro-2-bromo-1,3-propanediol; DTXSID8024652; beta-Bromo-beta-nitrotrimethyleneglycol

Regulatory listings held on file

Regulatory & Food Contact

FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS 2-Bromo-2-nitro-1,3-propanediol (CAS Reg. No. 52-51-7) As a preservative for boiler water additive formulations. For use only as a preservative in boiler water additive formulations. The food-contact substance shall be adde

GHS notification summary

0.1% (1 / 2149)

GHS hazard classification

GHS notification summary	0.1% (1 / 2149)
Reported hazard statements	H302, H312, H315, H318, H335, H400, H301 (14.4%), H331 (10%)

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H312: Harmful in contact with skin [Warning Acute toxicity, dermal]

What the public record says

Bronopol · CAS 52-51-7 · C3H6BrNO4. UNII 6PU1E16C9W. Boiling Point: 305.1 °F at 760 mmHg (NTP, 1992); Boiling Point: 130; Melting Point: 266 to 271 °F (NTP, 1992).

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.