2-溴-2-氯-1,1,1-三氟乙烷

Description

2-bromo-2-chloro-1,1,1-trifluoroethane · CAS 151-67-7 · C2HBrClF3. UNII UQT9G45D1P. Boiling Point: 122.4 °F at 760 mmHg (NTP, 1992); Boiling Point: 50.2; Boiling Point: 50.2 °C.

Identification

CAS Registry Number	151-67-7
PubChem CID	3562
Molecular formula	C2HBrClF3
IUPAC name	2-bromo-2-chloro-1,1,1-trifluoroethane
UNII (FDA)	UQT9G45D1P

Computed Descriptors

Molecular Weight	197.38
XLogP3	2.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	195.89022
Monoisotopic Mass	195.89022
Topological Polar Surface Area	0
Heavy Atom Count	7
Formal Charge	0

Physical & Chemical Properties

Boiling Point	122.4 °F at 760 mmHg (NTP, 1992)
Boiling Point	50.2
Boiling Point	50.2 °C
Boiling Point	50 °C
Boiling Point	122.4 °F
Boiling Point	122 °F
Melting Point	-180 °F (NIOSH, 2024)
Melting Point	50-50.5
Melting Point	-118 °C
Melting Point	-180 °F

Physical description & handling notes

• Halothane is a clear colorless highly volatile liquid with a sweet chloroform-like odor. Density 1.875 g / cm3. Boiling point 122.4 °F (50.2 °C). Noncombustible.
• Clear, colorless liquid with a sweetish, pleasant odor; inhalation anesthetic; [NIOSH]
• Liquid
• HIGHLY VOLATILE COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.
• Clear, colorless liquid with a sweetish, pleasant odor.
• Clear, colorless liquid with a sweetish, pleasant odor. [inhalation anesthetic]

Regulatory Status

GHS notification summary	6% (3 / 50)

GHS Hazard Classification

GHS notification summary	6% (3 / 50)
Reported hazard statements	H315 (84%), H318 (94%), H335 (84%), H341 (14%), H360 (84%), H319, H332, H336

Documented Uses

• For the induction and maintenance of general anesthesia
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Bromination of 2-chloro-1,1,2-trifluoroethylene to form 1,2-dibromo-1-chloro-1,2,2-trifluoroethane, isomerization of the product with anhydrous aluminum chloride to 1,1-dibromo-1-chloro-2,2,2-trifluoroethane, and reduction of the latter with hydrogen (catalyzed by platinum); the antimony chloride-catalysed reaction of hydrogen fluoride with 1,2-dibromo-1,1,2-trichloroethane.
• Preparation from a mixture of F3CCH2Cl and FCCBrCl: Suckling, Raventos, US 2921098 (1960 to I.C.I.); by rearrangement of F2BrCCHFCl: Scherer, Kuhn, US 2959624 (1960 to Hoechst); from BrClCHCBrCl2: Chapman, McGinty, GB 805764 (1958 to I.C.I.); from Br2ClCCF3: McGinty, US 3082263 (1963 to I.C.I.)
• ... /The use of chlorofluorocarbons for aerosol sprays/ was prohibited in 1979 except for a few specialized items, because of their depleting effect on stratospheric ozone. /Chlorofluorocarbons/
• Halothane is a potent volatile halogenated anesthetic gas that has been linked to many cases of idiosyncratic acute liver injury that are frequently severe. The potential of halothane to cause hepatotoxicity and the greater safety of newer anesthetics has led to a decrease in its use, currently limited to special situations, particularly in children. Because halothane is relatively inexpensive it continues to be used in developing countries.

Synonyms

halothane; 151-67-7; 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE; Fluothane; Narcotane; Narcotan; Rhodialothan; Anestan; Ftorotan; Fluorotane; Ftuorotan; Halothan; Narkotan; Fluktan; Halotan; Halsan

Frequently Asked Questions

What are the CAS number and molecular formula of 2-bromo-2-chloro-1,1,1-trifluoroethane?

CAS 151-67-7; molecular formula C2HBrClF3; molecular weight — g/mol.

What other names is 2-bromo-2-chloro-1,1,1-trifluoroethane known by?

halothane, 151-67-7, 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, Fluothane, Narcotane, Narcotan.

Is 2-bromo-2-chloro-1,1,1-trifluoroethane classified as hazardous?

6% of GHS notifications report no hazard classification (3 of 50).

What are the key physical properties of 2-bromo-2-chloro-1,1,1-trifluoroethane?

Boiling Point: 122.4 °F at 760 mmHg (NTP, 1992); Boiling Point: 50.2; Boiling Point: 50.2 °C; Boiling Point: 50 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.