2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride（CAS 3092-17-9）：分子式 C12H18N2O4、分子量 254.28；类别 有机化学品。
| CAS号 | 3092-17-9 |
|---|---|
| 分子式 | C12H18N2O4 |
| 分子量 | 254.28 |
| 熔点 | 200 |
| LogP | -0.5 |
| 应用领域 | Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >10、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Calculated removal (%): 45.4、Use Classification: Pharmaceuticals、Methods of Manufacturing: Synthesized from hydroquinone dimethyl ether by Friedel-Crafts acylation with chloroacetyl chloride、amination to the corresponding 2-aminoacetophenone、acylation at the amino function with chloroacetyl chloride、displacement of the chloro by the azido group and finally reduction with、e.g.、sodium borohydride and catalytic hydrogenation (Pd、C).、Formulations、Preparations: Table: Midodrine Hydrochloride Preparations [Table#7590] |
| 类别 | Organic Chemicals |
登记用途：Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >10、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Calculated removal (%): 45.4、Use Classification: Pharmaceuticals、Methods of Manufacturing: Synthesized from hydroquinone dimethyl ether by Friedel-Crafts acylation with chloroacetyl chloride、amination to the corresponding 2-aminoacetophenone、acylation at the amino function with chloroacetyl chloride、displacement of the chloro by the azido group and finally reduction with、e.g.、sodium borohydride and catalytic hydrogenation (Pd、C).、Formulations、Preparations: Table: Midodrine Hydrochloride Preparations [Table#7590]。
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride 是一种以碳骨架为基础的有机化合物，登记 CAS 号为 3092-17-9，分子式 C12H18N2O4（分子量 254.28），归属于有机化学品大类化工原料。
登记 CAS 号：3092-17-9
其分子式 C12H18N2O4 由 12 个碳、18 个氢、2 个氮、4 个氧 组成。
别名/同义词：2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride · midodrine hydrochloride
所属分类：有机化学品
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride 的 CAS 登记号为 3092-17-9。
分子式 C12H18N2O4，分子量 254.28。
别名/同义词：2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride、midodrine hydrochloride。
登记用途：Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >10、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Calculated removal (%): 45.4、Use Classification: Pharmaceuticals、Methods of Manufacturing: Synthesized from hydroquinone dimethyl ether by Friedel-Crafts acylation with chloroacetyl chloride、amination to the corresponding 2-aminoacetophenone、acylation at the amino function with chloroacetyl chloride、displacement of the chloro by the azido group and finally reduction with、e.g.、sodium borohydride and catalytic hydrogenation (Pd、C).、Formulations、Preparations: Table: Midodrine Hydrochloride Preparations [Table#7590]。
所属分类：Organic Chemicals。
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride（CAS 3092-17-9）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 3092-17-9 |
|---|---|
| PubChem CID | 4195 |
| Molecular formula | C12H18N2O4 |
| IUPAC name | 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide |
| UNII (FDA) | 6YE7PBM15H |
| Molecular Weight | 254.28 |
|---|---|
| XLogP3 | -0.6 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 6 |
| Exact Mass | 254.12665706 |
| Monoisotopic Mass | 254.12665706 |
| Topological Polar Surface Area | 93.8 |
| Heavy Atom Count | 18 |
| Melting Point | 200 |
|---|---|
| Melting Point | 150 °C |
| Melting Point | 200 - 203 °C |
| Solubility | 4.45e+00 g/L |
| LogP | -0.5 |
| LogP | 0.1 |
| Dissociation Constants | 7.8 |
midodrine; 42794-76-3; Midodrin; Midodrina; Midodrinum; Midodrinum [INN-Latin]; St 1085; ST-1085; 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol; DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid; 6YE7PBM15H; Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamid; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethylacetamide; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide; CHEBI:6933
| Reported hazard statements | H301 (97.6%) |
|---|
H301 (97.6%): Toxic if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride · CAS 3092-17-9 · C12H18N2O4. UNII 6YE7PBM15H. Melting Point: 200; Melting Point: 150 °C; Melting Point: 200 - 203 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride