2,3,5,6-Tetramethylpyrazine

Independent reference data for 2,3,5,6-Tetramethylpyrazine (CAS 1124-11-4), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional ClassesFlavoring Agents -> JECFA Flavorings Index

Synonyms and trade names

2,3,5,6-Tetramethylpyrazine; TETRAMETHYLPYRAZINE; 1124-11-4; Ligustrazine; Chuanxiongzine; Tetrapyrazine; chuanxingzine; FEMA No. 3237; CHUANXIONGQIN; TMPZ; 2,3,5,6,-Tetramethyl-1,4-pyrazine; DTXSID6047070; V80F4IA5XG; DTXCID4027070; NSC-36080; NSC-46451

Regulatory listings held on file

Regulatory & Food Contact	EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Cocoa, Coffee, Green, Mocha, Roast No safety concern at current levels of intake when used as a flavouring agent

GHS hazard classification

Reported hazard statements	H302 (100%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)

What the public record says

2,3,5,6-Tetramethylpyrazine is identified by CAS 1124-11-4, molecular formula C8H12N2 and molecular weight 136.10 g/mol. UNII V80F4IA5XG; ChEBI 133246; InChIKey FINHMKGKINIASC-UHFFFAOYSA-N. Boiling Point: 190.00 °C. @ 760.00 mm Hg; Boiling Point: 190 °C; Melting Point: 86 °C.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.