2-(1-萘甲基)-2-咪唑啉盐酸盐（CAS 550-99-2）：分子式 C14H14N2.ClH、分子量 246.73。
| CAS号 | 550-99-2 |
|---|---|
| 分子式 | C14H14N2.ClH |
| 分子量 | 246.73 |
| 熔点 | 255-260 °C |
| 应用领域 | Uses: THERAP CAT: Adrenergic (vasoconstrictor)、decongestant、Naphazoline、MEDICATION、The imidazoline derivative naphazoline、an alpha-2-adrenergic agonist、is used as non-prescription eye and nasal preparation because of its vasoconstrictive and decongestive properties.、Methods of Manufacturing: IN ALMOST QUANTITATIVE YIELDS BY HEATING 1-NAPHTHYLACETONITRILE WITH ETHYLENEDIAMINE MONOHYDROCHLORIDE @ 175 TO 200 °C FOR 1 HR. AMMONIA IS...BY-PRODUCT.、Formulations、Preparations: Ophthalmic: Solution: 0.012% All Clear ( with benzalkonium chloride)、(Bausch & Lomb)、Clear Eyes ( with benzalkonium chloride and glycerin 0.2%)、(Prestige Brands)、Naphcon ( with benzalkonium chloride)、(Alcon)、0.03% All Clear AR ( with benzalkonium chloride)、0.1% AK-Con ( with benzalkonium chloride)、(Akorn)、Albalon ( with benzalkonium chloride)、(Allergan)、Naphazoline Hydrochloride Ophthalmic Solution、(Bausch & Lomb).、Ophthalmic: Solution: 0.012% with Zinc Sulfate 0.25% Clear Eyes ACR ( with benzalkonium chloride and glycerin 0.2%)、0.025% with Pheniramine Maleate 0.3% Naphcon-A (with benzalkonium chloride)、(Alcon) Visine A、(Pfizer)、0.027% with Pheniramine Maleate 0.315% Opcon A、0.05% with Antazoline Phosphate 0.5% Vasocon-A ( with benzalkonium chloride)、(Novartis).、Trade names: Ak-Con (Akorn)、Albalon (Allergan)、Allerest Eye Drops (Pharmacraft)、Allergy Drops (Bausch & Lomb)、Clear Eyes (Ross)、Clera (Person and Covey)、Comfort Eye Drops、Degest 2 (Barnes-Hind)、Imidazyl (Allergan)、Naphcon (Alcon)、I-Naphline (Americal)、Opcon (Bausch & Lomb)、Optazine (Lederle)、Otrivin、Privin、Privina、Privine (Ciba)、Vasocon Regular (IOLAB). |
登记用途：Uses: THERAP CAT: Adrenergic (vasoconstrictor)、decongestant、Naphazoline、MEDICATION、The imidazoline derivative naphazoline、an alpha-2-adrenergic agonist、is used as non-prescription eye and nasal preparation because of its vasoconstrictive and decongestive properties.、Methods of Manufacturing: IN ALMOST QUANTITATIVE YIELDS BY HEATING 1-NAPHTHYLACETONITRILE WITH ETHYLENEDIAMINE MONOHYDROCHLORIDE @ 175 TO 200 °C FOR 1 HR. AMMONIA IS...BY-PRODUCT.、Formulations、Preparations: Ophthalmic: Solution: 0.012% All Clear ( with benzalkonium chloride)、(Bausch & Lomb)、Clear Eyes ( with benzalkonium chloride and glycerin 0.2%)、(Prestige Brands)、Naphcon ( with benzalkonium chloride)、(Alcon)、0.03% All Clear AR ( with benzalkonium chloride)、0.1% AK-Con ( with benzalkonium chloride)、(Akorn)、Albalon ( with benzalkonium chloride)、(Allergan)、Naphazoline Hydrochloride Ophthalmic Solution、(Bausch & Lomb).、Ophthalmic: Solution: 0.012% with Zinc Sulfate 0.25% Clear Eyes ACR ( with benzalkonium chloride and glycerin 0.2%)、0.025% with Pheniramine Maleate 0.3% Naphcon-A (with benzalkonium chloride)、(Alcon) Visine A、(Pfizer)、0.027% with Pheniramine Maleate 0.315% Opcon A、0.05% with Antazoline Phosphate 0.5% Vasocon-A ( with benzalkonium chloride)、(Novartis).、Trade names: Ak-Con (Akorn)、Albalon (Allergan)、Allerest Eye Drops (Pharmacraft)、Allergy Drops (Bausch & Lomb)、Clear Eyes (Ross)、Clera (Person and Covey)、Comfort Eye Drops、Degest 2 (Barnes-Hind)、Imidazyl (Allergan)、Naphcon (Alcon)、I-Naphline (Americal)、Opcon (Bausch & Lomb)、Optazine (Lederle)、Otrivin、Privin、Privina、Privine (Ciba)、Vasocon Regular (IOLAB).。
2-(1-萘甲基)-2-咪唑啉盐酸盐 是一种化工化合物，登记 CAS 号为 550-99-2，分子式 C14H14N2.ClH（分子量 246.73）。
登记 CAS 号：550-99-2
其分子式 C14H14N2.ClH 由 14 个碳、15 个氢、2 个氮、1 个氯 组成。
别名/同义词：2-(1-萘甲基)-2-咪唑啉盐酸盐 · 2-(1-Naphthylmethyl)-2-imidazoline hydrochloride
2-(1-萘甲基)-2-咪唑啉盐酸盐 的 CAS 登记号为 550-99-2。
分子式 C14H14N2.ClH，分子量 246.73。
别名/同义词：2-(1-萘甲基)-2-咪唑啉盐酸盐、2-(1-Naphthylmethyl)-2-imidazoline hydrochloride。
登记用途：Uses: THERAP CAT: Adrenergic (vasoconstrictor)、decongestant、Naphazoline、MEDICATION、The imidazoline derivative naphazoline、an alpha-2-adrenergic agonist、is used as non-prescription eye and nasal preparation because of its vasoconstrictive and decongestive properties.、Methods of Manufacturing: IN ALMOST QUANTITATIVE YIELDS BY HEATING 1-NAPHTHYLACETONITRILE WITH ETHYLENEDIAMINE MONOHYDROCHLORIDE @ 175 TO 200 °C FOR 1 HR. AMMONIA IS...BY-PRODUCT.、Formulations、Preparations: Ophthalmic: Solution: 0.012% All Clear ( with benzalkonium chloride)、(Bausch & Lomb)、Clear Eyes ( with benzalkonium chloride and glycerin 0.2%)、(Prestige Brands)、Naphcon ( with benzalkonium chloride)、(Alcon)、0.03% All Clear AR ( with benzalkonium chloride)、0.1% AK-Con ( with benzalkonium chloride)、(Akorn)、Albalon ( with benzalkonium chloride)、(Allergan)、Naphazoline Hydrochloride Ophthalmic Solution、(Bausch & Lomb).、Ophthalmic: Solution: 0.012% with Zinc Sulfate 0.25% Clear Eyes ACR ( with benzalkonium chloride and glycerin 0.2%)、0.025% with Pheniramine Maleate 0.3% Naphcon-A (with benzalkonium chloride)、(Alcon) Visine A、(Pfizer)、0.027% with Pheniramine Maleate 0.315% Opcon A、0.05% with Antazoline Phosphate 0.5% Vasocon-A ( with benzalkonium chloride)、(Novartis).、Trade names: Ak-Con (Akorn)、Albalon (Allergan)、Allerest Eye Drops (Pharmacraft)、Allergy Drops (Bausch & Lomb)、Clear Eyes (Ross)、Clera (Person and Covey)、Comfort Eye Drops、Degest 2 (Barnes-Hind)、Imidazyl (Allergan)、Naphcon (Alcon)、I-Naphline (Americal)、Opcon (Bausch & Lomb)、Optazine (Lederle)、Otrivin、Privin、Privina、Privine (Ciba)、Vasocon Regular (IOLAB).。
2-(1-萘甲基)-2-咪唑啉盐酸盐（CAS 550-99-2）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 550-99-2 |
|---|---|
| PubChem CID | 11079 |
| Molecular formula | C14H14N2.ClH |
| IUPAC name | 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole;hydrochloride |
| UNII (FDA) | MZ1131787D |
| Molecular Weight | 246.73 |
|---|---|
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 2 |
| Exact Mass | 246.0923762 |
| Monoisotopic Mass | 246.0923762 |
| Topological Polar Surface Area | 24.4 |
| Heavy Atom Count | 17 |
| Melting Point | 255-260 °C |
|---|---|
| Solubility | In water, 4.0X10+5 mg/L at 25 °C |
| Dissociation Constants | pKa = 10.35 (25 °C); pKa = 10.13 (35 °C); pKa = 9.92 (45 °C) |
| Other Experimental Properties | DECOMP @ 253-258 °C |
NAPHAZOLINE HYDROCHLORIDE; 550-99-2; NAPHAZOLINE HCL; Albalon; Vasocon; Opcon; Rhinantin; Rhinoperd; Stricylon; Niazol; Naphcon forte; Privine hydrochloride; Naphazoline chloride; Coldan; Sanorin; Prizole hydrochloride
| Reported hazard statements | H300 (86.3%) |
|---|
H300 (86.3%): Fatal if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)
2-(1-Naphthylmethyl)-2-imidazoline hydrochloride · CAS 550-99-2 · C14H14N2.ClH. UNII MZ1131787D. Melting Point: 255-260 °C; Solubility: In water, 4.0X10+5 mg/L at 25 °C; Dissociation Constants: pKa = 10.35 (25 °C); pKa = 10.13 (35 °C); pKa = 9.92 (45 °C).
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: 2-(1-Naphthylmethyl)-2-imidazoline hydrochloride