17α-Hydroxyprogesterone (CAS 68-96-2) — formula C21H30O3, molecular weight 330.5.
| CAS Number | 68-96-2 |
|---|---|
| Molecular Formula | C21H30O3 |
| Molecular Weight | 330.5 |
| Melting Point | 222-223 °C |
| LogP | 3.17 |
| Applications | Uses: MEDICATION (VET), MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 17.2, This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation., Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: HYDROXYPROGESTERONE IS ESTERIFIED BY HEATING WITH CAPROIC ANHYDRIDE IN PRESENCE OF P-TOLUENE-SULFONIC ACID UNDER ATMOSPHERE OF NITROGEN. US PATENT 2, 753, 360., CAPROATE, JULIAN ET AL, US PATENT 2, 648, 662 (1953 TO GLIDDEN)...STORK ET AL, US PATENTS 2, 802, 839 & 2, 805, 203 (BOTH 1957 TO SYNTEX)...DULANEY, MCALEER, 777, 843, 2, 786, 856, 7, 813, 060 (ALL 1957 TO MERCK & CO)...PEDERSON, US PATENT 3, 000, 883 (1961 TO UPJOHN)., Formulations, Preparations: HYDROXYPROGESTERONE CAPROATE INJECTION, USP (DELALUTIN), IS PROVIDED AS OILY SOLN OF 125 MG, ML (IN SESAME OIL) OR 250 MG, ML (IN CASTOR OIL) FOR IM INJECTION., General Manufacturing Information: PROGESTINS CANNOT BE EQUATED AS GROUP WITH PROGESTERONE BECAUSE SOME ARE INHERENTLY ESTROGENIC, SOME SLIGHTLY ANDROGENIC, & SOME PURELY PROGESTATIONAL, CORRESPONDINGLY, THEIR OVULATION-INHIBITING POTENTIALITIES MAY BE MEDIATED IN SOMEWHAT DIFFERENT WAYS., PROGESTINS |
Documented applications: Uses: MEDICATION (VET), MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 17.2, This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation., Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: HYDROXYPROGESTERONE IS ESTERIFIED BY HEATING WITH CAPROIC ANHYDRIDE IN PRESENCE OF P-TOLUENE-SULFONIC ACID UNDER ATMOSPHERE OF NITROGEN. US PATENT 2, 753, 360., CAPROATE, JULIAN ET AL, US PATENT 2, 648, 662 (1953 TO GLIDDEN)...STORK ET AL, US PATENTS 2, 802, 839 & 2, 805, 203 (BOTH 1957 TO SYNTEX)...DULANEY, MCALEER, 777, 843, 2, 786, 856, 7, 813, 060 (ALL 1957 TO MERCK & CO)...PEDERSON, US PATENT 3, 000, 883 (1961 TO UPJOHN)., Formulations, Preparations: HYDROXYPROGESTERONE CAPROATE INJECTION, USP (DELALUTIN), IS PROVIDED AS OILY SOLN OF 125 MG, ML (IN SESAME OIL) OR 250 MG, ML (IN CASTOR OIL) FOR IM INJECTION., General Manufacturing Information: PROGESTINS CANNOT BE EQUATED AS GROUP WITH PROGESTERONE BECAUSE SOME ARE INHERENTLY ESTROGENIC, SOME SLIGHTLY ANDROGENIC, & SOME PURELY PROGESTATIONAL, CORRESPONDINGLY, THEIR OVULATION-INHIBITING POTENTIALITIES MAY BE MEDIATED IN SOMEWHAT DIFFERENT WAYS., PROGESTINS.
17α-Hydroxyprogesterone is a chemical compound with CAS registry number 68-96-2 and molecular formula C21H30O3 (molecular weight 330.5).
CAS number: 68-96-2
Its molecular formula C21H30O3 comprises 21 C, 30 H, 3 O atoms.
Also known as: 17α-Hydroxyprogesterone · 17α-羟基孕酮 · 17A-hydroxyprogesterone
The CAS registry number of 17α-Hydroxyprogesterone is 68-96-2.
Molecular formula C21H30O3, molecular weight 330.5.
It is also registered under: 17α-Hydroxyprogesterone, 17α-羟基孕酮, 17A-hydroxyprogesterone.
Recorded applications: Uses: MEDICATION (VET), MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 17.2, This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation., Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: HYDROXYPROGESTERONE IS ESTERIFIED BY HEATING WITH CAPROIC ANHYDRIDE IN PRESENCE OF P-TOLUENE-SULFONIC ACID UNDER ATMOSPHERE OF NITROGEN. US PATENT 2, 753, 360., CAPROATE, JULIAN ET AL, US PATENT 2, 648, 662 (1953 TO GLIDDEN)...STORK ET AL, US PATENTS 2, 802, 839 & 2, 805, 203 (BOTH 1957 TO SYNTEX)...DULANEY, MCALEER, 777, 843, 2, 786, 856, 7, 813, 060 (ALL 1957 TO MERCK & CO)...PEDERSON, US PATENT 3, 000, 883 (1961 TO UPJOHN)., Formulations, Preparations: HYDROXYPROGESTERONE CAPROATE INJECTION, USP (DELALUTIN), IS PROVIDED AS OILY SOLN OF 125 MG, ML (IN SESAME OIL) OR 250 MG, ML (IN CASTOR OIL) FOR IM INJECTION., General Manufacturing Information: PROGESTINS CANNOT BE EQUATED AS GROUP WITH PROGESTERONE BECAUSE SOME ARE INHERENTLY ESTROGENIC, SOME SLIGHTLY ANDROGENIC, & SOME PURELY PROGESTATIONAL, CORRESPONDINGLY, THEIR OVULATION-INHIBITING POTENTIALITIES MAY BE MEDIATED IN SOMEWHAT DIFFERENT WAYS., PROGESTINS.
Independent reference data for 17α-Hydroxyprogesterone (CAS 68-96-2), compiled from public chemistry databases.
| CAS Registry Number | 68-96-2 |
|---|---|
| PubChem CID | 6238 |
| Molecular formula | C21H30O3 |
| IUPAC name | (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one |
| UNII (FDA) | 21807M87J2 |
| Molecular Weight | 330.5 |
|---|---|
| XLogP3 | 3.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 330.21949481 |
| Monoisotopic Mass | 330.21949481 |
| Topological Polar Surface Area | 54.4 |
| Heavy Atom Count | 24 |
| Melting Point | 222-223 °C |
|---|---|
| Melting Point | 219 - 220 °C |
| Solubility | 0.00648 mg/mL |
| LogP | 3.17 |
| Collision Cross Section | 187 Ų [M-H]- |
| Collision Cross Section | 186.4 Ų [M+H]+ |
| Collision Cross Section | 208.9 Ų [M+Na]+ |
hydroxyprogesterone; 68-96-2; 17ALPHA-HYDROXYPROGESTERONE; 17-Hydroxyprogesterone; Prodix; Prodox; Gestageno gador; 17-alpha-Hydroxyprogesterone; 17-Hydroxypregn-4-ene-3,20-dione; Gestageno; Hidroxiprogesterona; Hydroxyprogesteronum; 17alpha-Hydroxy-4-pregnene-3,20-dione; 17-OH Progesterone; delta(4)-Pregnene-17alpha-ol-3,20-dione; 17alpha-Hydroxy-progesterone
| Reported hazard statements | H360 (95.1%) |
|---|
H360 (95.1%): May damage fertility or the unborn child [Danger Reproductive toxicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
17A-hydroxyprogesterone · CAS 68-96-2 · C21H30O3. UNII 21807M87J2. Melting Point: 222-223 °C; Melting Point: 219 - 220 °C; Solubility: 0.00648 mg/mL.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 17α-羟基孕酮