10-炔丙基-10-脱氮氨基蝶呤（CAS 146464-95-1）：分子式 C23H23N7O5、分子量 477.5。
| CAS号 | 146464-95-1 |
|---|---|
| 分子式 | C23H23N7O5 |
| 分子量 | 477.5 |
| LogP | -0.9 |
| 应用领域 | Uses: MEDICATION、Pralatrexate is indicated for the treatment of ... relapsed or refractory peripheral T-cell lymphoma (PTCL).、Included in US product label、Formulations、Preparations: FOLOTYN (pralatrexate) is available in sterile、single-use vials containing pralatrexate at a concentration of 20 mg、mL in the following presentations: 20 mg of pralatrexate in 1 mL solution in a vial (20 mg、1 mL)、40 mg of pralatrexate in 2 mL solution in a vial (40 mg、2 mL). |
登记用途：Uses: MEDICATION、Pralatrexate is indicated for the treatment of ... relapsed or refractory peripheral T-cell lymphoma (PTCL).、Included in US product label、Formulations、Preparations: FOLOTYN (pralatrexate) is available in sterile、single-use vials containing pralatrexate at a concentration of 20 mg、mL in the following presentations: 20 mg of pralatrexate in 1 mL solution in a vial (20 mg、1 mL)、40 mg of pralatrexate in 2 mL solution in a vial (40 mg、2 mL).。
10-炔丙基-10-脱氮氨基蝶呤 是一种化工化合物，登记 CAS 号为 146464-95-1，分子式 C23H23N7O5（分子量 477.5）。
登记 CAS 号：146464-95-1
其分子式 C23H23N7O5 由 23 个碳、23 个氢、7 个氮、5 个氧 组成。
别名/同义词：10-炔丙基-10-脱氮氨基蝶呤 · 10-Propargyl-10-deazaaminopterin
10-炔丙基-10-脱氮氨基蝶呤 的 CAS 登记号为 146464-95-1。
分子式 C23H23N7O5，分子量 477.5。
别名/同义词：10-炔丙基-10-脱氮氨基蝶呤、10-Propargyl-10-deazaaminopterin。
登记用途：Uses: MEDICATION、Pralatrexate is indicated for the treatment of ... relapsed or refractory peripheral T-cell lymphoma (PTCL).、Included in US product label、Formulations、Preparations: FOLOTYN (pralatrexate) is available in sterile、single-use vials containing pralatrexate at a concentration of 20 mg、mL in the following presentations: 20 mg of pralatrexate in 1 mL solution in a vial (20 mg、1 mL)、40 mg of pralatrexate in 2 mL solution in a vial (40 mg、2 mL).。
10-炔丙基-10-脱氮氨基蝶呤（CAS 146464-95-1）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 146464-95-1 |
|---|---|
| PubChem CID | 148121 |
| Molecular formula | C23H23N7O5 |
| IUPAC name | (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid |
| UNII (FDA) | A8Q8I19Q20 |
| Molecular Weight | 477.5 |
|---|---|
| XLogP3 | -0.9 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 10 |
| Exact Mass | 477.17606686 |
| Monoisotopic Mass | 477.17606686 |
| Topological Polar Surface Area | 207 |
| Heavy Atom Count | 35 |
Pralatrexate; 146464-95-1; Folotyn; 10-Propargyl-10-deazaaminopterin; pralatrexato; HSDB 7786; N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid; pralatrexatum; DTXSID3048578; NSC-754230; CHEBI:71223; A8Q8I19Q20; (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid; (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid; DTXCID3028504; N-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-L-glutamic acid
| Reported hazard statements | H301 (66.7%), H311 (16.7%), H315 (33.3%), H319 (16.7%), H331 (16.7%), H335 (16.7%), H340 (16.7%), H351 (16.7%) |
|---|
H301 (66.7%): Toxic if swallowed [Danger Acute toxicity, oral]
H311 (16.7%): Toxic in contact with skin [Danger Acute toxicity, dermal]
10-Propargyl-10-deazaaminopterin · CAS 146464-95-1 · C23H23N7O5. UNII A8Q8I19Q20.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: 10-Propargyl-10-deazaaminopterin